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Chiroptical detection during liquid chromatography 3: Non-stop acquisition of circular dichroism spectra during liquid chromatography

Brandl, Gert ; Kastner, F. ; Mannschreck, Albrecht ; Nölting, B. ; Andert, K. ; Wetzel, R.



Abstract

A new type of spectrometer, built in-house, served as a circular dichroism detector for liquid chromatography. It acquired differential absorbances ΔA = f(λ) at all wavelengths, λ, between 208 and 268 nm simultaneously within a time interval of 9 s. Non-stop acquisition of circular dichroism spectra during liquid chromatography is described for the first time. The novel set-up gives automatic ...

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