The influence of cold shock proteins on transcription and translation studied in cell-free model systems

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.1878

Hofweber, Roland ; Horn, Gudrun ; Langmann, Thomas ; Balbach, Jochen ; Kremer, Werner ; Schmitz, Gerd ; Kalbitzer, Hans-Robert

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Veröffentlichungsdatum dieses Volltextes: 05 Aug 2009 13:34

Alternative Links zum Volltext:DOI Verlag

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Cold shock proteins (CSPs) form a family of highly conserved bacterial proteins capable of single-stranded nucleic acid binding. They are suggested to act as RNA chaperones during cold shock inhibiting the formation of RNA secondary structures, which are unfavourable for transcription and translation. To test this commonly accepted theory, isolated CSPs from a mesophilic, thermophilic and a ...