Potencies of topical glucocorticoids to mediate genomic and nongenomic effects on human peripheral blood mononuclear cells

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.1952

Naumann, Lydia ; Feist, Eugen ; Straub, Rainer H. ; Burmester, Gerd-Rüdiger ; Buttgereit, Frank

PDF
(433kB) - Nur für Mitarbeiter des Archivs

Veröffentlichungsdatum dieses Volltextes: 05 Aug 2009 13:35

Alternative Links zum Volltext:Pubmed DOI Verlag

Details

Bibliographische Daten exportieren

Zusammenfassung

Several different genomic and nongenomic mechanisms are known to mediate the important anti-inflammatory and immunomodulatory effects of glucocorticoids (GC). Genomic effects are the most important while the clinical relevance of nongenomic actions is still a matter of debate. We therefore investigated whether beclometasone and clobetasol are particularly suitable for topical application because ...