A partially automated radioligand binding assay system for use in clinical and pharmaceutical research

URN to cite this document:: urn:nbn:de:bvb:355-epub-196330
DOI to cite this document:: 10.5283/epub.19633

Liebl, B. ; Anhäupl, T. ; Haen, Ekkehard ; Günster, B. ; Georgieff, M.

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Date of publication of this fulltext: 18 Feb 2011 10:09

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Abstract

Using a Tecan robotic sample processor and IBM compatible PCs we have developed a flexible, partially automated radioligand binding assay system. It handles pipetting parameters of up to 16 saturation or competition experiments at a time with up to 24 radioligand- or competitor-concentrations in a range over 4 orders of magnitude per experiment. The system provides enough flexibility so that all ...