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Quantitation of mRNA for the beta-adrenoceptor gene in human mononuclear leucocytes by in situ hybridization with fluorochrome labeled cloned DNA

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Liebl, B. ; Pachmann, K. ; Römer, U. ; Haen, Ekkehard ; Hallek, M. ; Emmerich, B.
Date of publication of this fulltext: 18 Feb 2011 10:23


Determination of the transcriptional activity of the beta-adrenoceptor (beta-AR) gene in human mononuclear leucocytes (MNL) may provide important information concerning variations in receptor expression in clinical studies. We used a new method with highly fluorochrome-labeled gene probes for in situ hybridization which allows a rapid detection of mRNA at the cellular level. MNL from venous blood ...


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