Circannual variation in the expression of beta 2-adrenoceptors on human peripheral mononuclear leukocytes (MNLs)

URN to cite this document:: urn:nbn:de:bvb:355-epub-196432
DOI to cite this document:: 10.5283/epub.19643

Haen, Ekkehard ; Langenmayer, I. ; Pangerl, A. ; Liebl, B. ; Remien, J.

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Date of publication of this fulltext: 18 Feb 2011 09:54

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Abstract

Peripheral mononuclear leukocytes (MNLs) are widely used as a tissue model in studies of beta-adrenoceptor disturbances in hypertension and asthmatic diseases. The beta 2-adrenoceptor density (Bmax), however, depends not only on the gender of the person under study and on the time of day the blood specimens are obtained. Evidence is now reported for a circannual variation in the expression of ...