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Impairment of the beta-adrenergic system of peripheral-blood leukocytes in atopic patients with seasonal allergic rhinoconjunctivitis

URN to cite this document:
urn:nbn:de:bvb:355-epub-197891
Haen, Ekkehard ; Bleise, Ute ; Przybilla, W.
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Date of publication of this fulltext: 11 Mar 2011 06:40


Abstract

Compared to 7 healthy women, an altered beta2-adrenoceptor/cyclic adenosine monophosphate (cAMP) system has been observed in a combined study on both expression and function of beta2-adrenoceptors on peripheral blood leukocytes (PBL) of 7 atopic women suffering from acute seasonal rhinoconjunctivitis. A reduced affinity of the beta-adrenergic radioligand I-125 cyanopindolol to its binding site ...

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