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Is there a relationship between response to total sleep deprivation and efficacy of clomipramine treatment in depressed patients?

URN to cite this document:
Höchli, D. ; Riemann, D. ; Zulley, Jürgen ; Berger, M.
Date of publication of this fulltext: 29 Apr 2011 09:10


Total sleep deprivation (TSD) and tricyclic medication are successful treatment modalities for patients with a major depressive disorder. Recent studies have suggested a positive relationship between TSD response and succeeding tricyclic treatment, even on a very specific level, thus supporting the assumption of two distinct biochemical subtypes of depression. The present study tested this ...


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