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Influence of the cholinergic agonist RS 86 on normal sleep: sex and age effects

Riemann, D., Joy, D., Höchli, D., Lauer, C., Zulley, Jürgen and Berger, M. (1988) Influence of the cholinergic agonist RS 86 on normal sleep: sex and age effects. Psychiatry research 24 (2), pp. 137-147.

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Abstract

In 36 healthy control subjects (21 females, 15 males; age range 18-65 years; mean age 41.8 years, SD 15.6 years), a bedtime dose of 1.5 mg RS 86, an orally acting cholinergic agonist, shortened rapid eye movement (REM) latency, increased REM sleep, and decreased slow-wave sleep. Six of the subjects (greater than 40 years old) even displayed sleep-onset REM periods after the drug. Results of the ...

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Item type:Article
Date:1988
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
3406234PubMed ID
10.1016/0165-1781(88)90056-XDOI
Classification:
NotationType
AdolescentMESH
AdultMESH
Affect/drug effectsMESH
AgedMESH
Aging/physiologyMESH
FemaleMESH
HumansMESH
MaleMESH
Middle AgedMESH
Parasympathomimetics/pharmacologyMESH
Reaction Time/physiologyMESH
Sex FactorsMESH
Sleep/physiologyMESH
Sleep, REM/physiologyMESH
Succinimides/pharmacologyMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Item ID:19872
Owner only: item control page

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