Go to content
UR Home

Comparison of a Nucleosidic vs Non-Nucleosidic Postsynthetic “Click” Modification of DNA with Base-Labile Fluorescent Probes

URN to cite this document:
urn:nbn:de:bvb:355-epub-200430
DOI to cite this document:
10.5283/epub.20043
Berndl, Sina ; Herzig, Nadine ; Kele, Péter ; Lachmann, Daniel ; Li, Xiaohua ; Wolfbeis, Otto S. ; Wagenknecht, Hans-Achim
[img]
Preview
PDF
(272kB)
Date of publication of this fulltext: 18 Mar 2011 07:12


Abstract

The azides 1 and 2 bearing a phenoxazinium and a coumarin fluorophore, respectively, were applied in postsynthetic "click"-type bioconjugation and coupled to oligonucleotides modified with alkyne groups using two alternative approaches: (i) as a nucleotide modification at the 2'-position of uridine and (ii) as a nucleotide substitution using (S)-(-)-3-amino-l,2-propanediol as an acyclic linker ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons