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Sensitive luminescent determination of DNA using the terbium(III)–difloxacin complex

Yegorova, Alla V., Scripinets, Yulia V., Dürkop, Axel, Karasyov, Alexander A., Antonovich, Valery P. and Wolfbeis, Otto S. (2007) Sensitive luminescent determination of DNA using the terbium(III)–difloxacin complex. Analytica Chimica Acta 584 (2), pp. 260-267.

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The interaction of the terbium–difloxacin complex (Tb–DFX) with DNA has been examined by using UV–vis absorption and luminescence spectroscopy. The Tb–DFX complex shows an up to 85-fold enhancement of luminescence intensity upon titration with DNA. The long decay times allow additional detection schemes like time-resolved measurements in microplate readers to enhance sensitivity by off-gating ...


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Item type:Article
Date:19 February 2007
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
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Keywords:UV–vis spectrometry; Luminescence; Terbium; Quinolones; Difloxacin; DNA
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Created at the University of Regensburg:Unknown
Item ID:20200
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