Sensitive luminescent determination of DNA using the terbium(III)–difloxacin complex

DOI to cite this document:: 10.5283/epub.20200

Yegorova, Alla V. ; Scripinets, Yulia V. ; Dürkop, Axel

; Karasyov, Alexander A. ; Antonovich, Valery P. ; Wolfbeis, Otto S.

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Date of publication of this fulltext: 18 Mar 2011 08:05

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Abstract

The interaction of the terbium-difloxacin complex (Tb-DFX) with DNA has been examined by using UV-vis absorption and luminescence spectroscopy. The Tb-DFX complex shows an up to 85-fold enhancement of luminescence intensity upon titration with DNA. The long decay times allow additional detection schemes like time-resolved measurements in microplate readers to enhance sensitivity by off-gating ...