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The Click Reaction in the Luminescent Probing of Metal Ions, and Its Implications on Biolabeling Techniques

Wolfbeis, Otto S.
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Date of publication of this fulltext: 18 Mar 2011 08:07


Copper concentrations at a click: The copper(I)-catalyzed Huisgen cycloaddition (the “click reaction”) enables micromolar concentrations of physiologically active Cu+ ions to be sensed through photonic energy transfer (ET, see scheme), and offers great potential in terms of labeling methods.

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