Modification of HLA expression as a possible factor in the pathogenesis of Burkitt's lymphoma

URN to cite this document:: urn:nbn:de:bvb:355-epub-205205

Voltz, R. ; Jilg, Wolfgang ; Wolf, Hans J.

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Date of publication of this fulltext: 18 Apr 2011 11:31

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Abstract

Our data show that: Most BL cells express significantly less HLA class I and II than the corresponding LCLs. Lymphoblastoid cell lines have a much higher HLA class I and II density than normal peripheral blood B cells. There are qualitative differences in class I and II expression in most BL/LCL pairs. These qualitative differences are not caused by EBV infection. They might be due to a selective ...