Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions

URN to cite this document:: urn:nbn:de:bvb:355-epub-205380
DOI to cite this document:: 10.5283/epub.20538

Modrow, Susanne ; Hahn, B. H. ; Shaw, G. M. ; Gallo, R. C. ; Wong-Staal, F. ; Wolf, Hans J.

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Date of publication of this fulltext: 15 Apr 2011 08:46

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Abstract

Independent isolates of human immunodeficiency virus (HIV) exhibit a striking genomic diversity, most of which is located in the viral envelope gene. Since this property of the HIV group of viruses may play an important role in the pathobiology of the virus, we analyzed the predicted amino acid sequences of the envelope proteins of seven different HIV strains, three of which represent sequential ...