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Surfactant substitution in ventilated very low birth weight infants: factors related to response types

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Segerer, Hugo ; Stevens, P. ; Schadow, B. ; Maier, R. ; Kattner, E. ; Schwarz, H. ; Curstedt, T. ; Robertson, B. ; Obladen, Michael
Date of publication of this fulltext: 11 May 2011 05:53


We investigated factors than may influence the response to surfactant substitution. Thirty-five very low birth weight infants with respiratory distress syndrome were treated with Curosurf at 3-12 h of age. From the changes in oxygenation, the therapeutic response was categorized as rapid and sustained, rapid with relapse, or poor. Phospholipids and surfactant protein A were quantified in gastric ...


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