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Optimization of capacitive affinity sensors: drift suppression and signal amplification

DOI to cite this document:
Riepl, Michael ; Mirsky, Vladimir M. ; Novotny, Ivan ; Tvarozek, Vladimir ; Rehacek, Vlastimil ; Wolfbeis, Otto S.
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Date of publication of this fulltext: 06 Jun 2011 13:36


The detection limit of capacitive affinity sensors based on the gold±alkanethiol system can be improved by optimization of sensor preparation and by signal amplification. The dissociation of the gold±sulfur binding is often a critical point leading to operative errors of such sensors. The stability of self-assembled monolayers prepared with different thiols on gold electrodes in aqueous and ...


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