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Luminescent single and dual sensors for in vivo imaging of pH and pO2

Meier, Robert Johannes (2011) Luminescent single and dual sensors for in vivo imaging of pH and pO2. PhD, Universität Regensburg.

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Date of publication of this fulltext: 05 Aug 2011 09:12

Abstract (English)

This thesis describes the development and characterization of novel optical sensor materials for clinical in vivo applications. At first, biocompatible single- and dual sensors for the clinically important parameters pH and pO2 were realized using a time-resolved read-out. For the first time, spatial pH and/or pO2 distributions in cutaneous and chronic wounds of humans were visualized. Further, a ...

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Translation of the abstract (German)

Diese Dissertation beschreibt die Entwicklung und Charakterisierung neuartiger optischer Sensormaterialien für klinische in vivo-Anwendungen. Zunächst wurden zeitaufgelöst auslesbare Einzel- und Dual-Sensoren für die klinisch relevanten Parameter pH und pO2 entwickelt. Durch diese Sensoren konnte zum ersten Mal die räumliche Verteilung der pH- und/oder Sauerstoff-Werte in kutanen und chronischen ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:5 August 2011
Referee:Prof. Dr. Otto S. Wolfbeis and Prof. Dr. Joachim Wegener
Date of exam:7 July 2011
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
Interdisciplinary Subject Network:Not selected
Keywords:RGB, Imaging, in vivo, human tissue, lifetime, fluorescence, luminescence, skin, analytical chemistry, RLD, tdDLR, time-gated
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:21075
Owner only: item control page

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