Sol–gel based glucose biosensors employing optical oxygen transducers, and a method for compensating for variable oxygen background

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.21086

Wolfbeis, Otto S. ; Oehme, Ines ; Papkovskaya, Natalya ; Klimant, Ingo

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Veröffentlichungsdatum dieses Volltextes: 06 Jun 2011 12:48

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Various types of thin-film glucose biosensors based on the use of the enzyme glucose oxidase (GOx) have been developed. The luminescent oxygen probe Ru(dpp) — whose emission is quenched by oxygen — is used to measure the consumption of oxygen. Three different combinations of oxygen transducer and sol–gel immobilized GOx were tested. In the first, GOx was sandwiched between a sol–gel layer doped ...