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Capacitive monitoring of protein immobilization and antigen–antibody reactions on monomolecular alkylthiol films on gold electrodes

Mirsky, Vladimir M., Riepl, Michael and Wolfbeis, Otto S. (1997) Capacitive monitoring of protein immobilization and antigen–antibody reactions on monomolecular alkylthiol films on gold electrodes. Biosensors and Bioelectronics 12 (9-10), pp. 977-989.

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Date of publication of this fulltext: 06 Jun 2011 13:48

Abstract

Self-assembled monolayers of v-mercaptohexadecanoic acid and vmercaptohexadecylamine on gold electrodes are stable at neutral pH and display pure capacitive behavior at frequencies around 20 Hz. Different methods of covalent immobilization of proteins on these monolayers are compared. Various reagents including succinimides, thionylchloride, p-nitrophenol and carbodiimides were used to activate ...

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Item type:Article
Date:1997
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
Keywords:protein immobilization, self-assembly, immunosensor, impedance, capacitive sensors
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Item ID:21088
Owner only: item control page

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