Perioperative uses of histamine antagonists

URN to cite this document:: urn:nbn:de:bvb:355-epub-217667
DOI to cite this document:: 10.5283/epub.21766

Lorenz, Wilfried ; Ennis, M. ; Doenicke, A. ; Dick, W.

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Date of publication of this fulltext: 16 Aug 2011 06:19

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Abstract

Histamine release and adverse pseudoallergic/allergic reactions during the perioperative period occur frequently. The incidence of such reactions is 20%-30% for all grades of severity, 1%-5% for systemic reactions, and 0.1%-0.5% for life-threatening reactions. They can be elicited by all commonly used anesthetic agents and by surgical interventions. Both the incidence and severity can be reduced ...