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Significance of histamine formation and release in the development of endotoxic shock: proof of current concepts by randomized controlled studies in rats

Neugebauer, E., Lorenz, Wilfried, Beckurts, T., Maroske, D. and Merte, H. (1987) Significance of histamine formation and release in the development of endotoxic shock: proof of current concepts by randomized controlled studies in rats. Reviews of infectious diseases 9 Supp, S585-S593.

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Abstract

The significance of histamine in the initiation and progression of septic (endotoxic) shock is still uncertain. Increased new formation and increased release of histamine are the two hypotheses currently considered as the basis for a causal relationship. Both hypotheses were tested in a standardized rat model of endotoxic shock. Several randomized controlled studies were performed with inhibitors ...

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Item type:Article
Date:1987
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
2446370PubMed ID
Classification:
NotationType
AnimalsMESH
Disease Models, AnimalMESH
Histamine/biosynthesisMESH
Histamine ReleaseMESH
Models, BiologicalMESH
Random AllocationMESH
RatsMESH
Shock, Septic/etiologyMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:21783
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