Histaminolibération induite par les produits anesthésiques ou leurs solvants : spécifique ou non spécifique ? [Histamine liberation induced by anesthetics or their solvents: specific or non-specific?]

URN to cite this document:

urn:nbn:de:bvb:355-epub-218047 Copy

DOI to cite this document:

10.5283/epub.21804 Copy

Lorenz, Wilfried ; Doenicke, A.

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Date of publication of this fulltext: 19 Aug 2011 11:21

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Details

Item type:	Article
Journal or Publication Title:	Annales françaises d'anesthèsie et de rèanimation
Publisher:	Masson (Paris); Elsevier
Volume:	4
Number of Issue or Book Chapter:	2
Page Range:	pp. 115-123
Date:	1985
Institutions:	Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:	Value Type 2408507 PubMed ID
Classification:	Notation Type Anesthetics/pharmacology MESH Anesthetics, Local/pharmacology MESH Histamine/blood MESH Histamine Antagonists MESH Histamine Release/drug effects MESH Humans MESH Intraoperative Period MESH Morphine/pharmacology MESH Neuromuscular Blocking Agents/pharmacology MESH Postoperative Period MESH Preanesthetic Medication MESH Receptors, Histamine/drug effects MESH Solvents/pharmacology MESH Succinylcholine/pharmacology MESH
Dewey Decimal Classification:	600 Technology > 610 Medical sciences Medicine
Status:	Published
Refereed:	Yes, this version has been refereed
Created at the University of Regensburg:	Unknown
Item ID:	21804

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Abstract

Histamine release is a frequent event in the perioperative period. The reasons for its occurrence are complex; they include pseudoallergic and allergic phenomena--and probably a mixture of both. Some drugs and solvents seem to modulate histamine release induced by other drugs. Thus the terms "specific and nonspecific" or "selective and nonselective" histamine release which have their well ...

Abstract

Histamine release is a frequent event in the perioperative period. The reasons for its occurrence are complex; they include pseudoallergic and allergic phenomena--and probably a mixture of both. Some drugs and solvents seem to modulate histamine release induced by other drugs. Thus the terms "specific and nonspecific" or "selective and nonselective" histamine release which have their well appreciated place in experimental immunology and pharmacology should be avoided in describing histamine release responses in clinical conditions. The clinical relevance of histamine release in the perioperative period is considerable and can be compared with that of perioperative thrombosis and thromboembolism. Far too many drugs and anaesthetic and surgical procedures give increased plasma histamine levels; premedication with H1- + H2-histamine receptor antagonists is therefore recommended in patients who have a history of hypersensitivity reactions to intravenous agents; a history of atopy, who are to be given the same drug a few days later, undergo surgery with a high risk of histamine release, are more than 70 years old or are poor risk patients with perioperative cardiac, respiratory or liver failure and shock.

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