Metabolism and function of gastric histamine in health and disease

URN to cite this document:: urn:nbn:de:bvb:355-epub-218652
DOI to cite this document:: 10.5283/epub.21865

Lorenz, Wilfried ; Thon, K. ; Barth, H. ; Neugebauer, E. ; Reimann, H. J. ; Kusche, J.

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Date of publication of this fulltext: 22 Aug 2011 14:11

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Abstract

Histamine is not uniformly distributed in the human and animal organisms, but occurs in high concentrations in the gastric mucosa. The enzymes responsible for its metabolism--histidine decarboxylase, histamine N-methyltransferase and diamine oxidase--seem to be less predominantly localized in the stomach. Considerable effort was necessary to detect and measure histamine formation in the gastric ...