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Histamine release after intravenous application of short-acting hypnotics. A comparison of etomidate, Althesin (CT1341) and propanidid

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DOI to cite this document:
Doenicke, A. ; Lorenz, Wilfried ; Beigl, R. ; Bezecny, H. ; Uhlig, G. ; Kalmar, L. ; Praetorius, B. ; Mann, G.
Date of publication of this fulltext: 24 Aug 2011 10:21


The subject of histamine release was investigated in 16 volunteers by means of plasma histamine determination after the administration of etornidate, Althesin, propanidid, and Cremophor EL. Althesin and propanidid caused release of histamine in various degrees of frequency. Blood pressure changes were rather pronounced with both anaesthetic agents; tachycardia reached its maximum in the first and ...


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