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Histamine release in man by propanidid and thiopentone: pharmacological effects and clinical consequences

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Lorenz, Wilfried ; Doenicke, A. ; Meyer, R. ; Reimann, H. J. ; Kusche, J. ; Barth, H. ; Geesing, H. ; Hutzel, M. ; Weissenbacher, B.
Date of publication of this fulltext: 24 Aug 2011 09:54


Using a new, highly sensitive and specific method for the determination of histamine in human plasma, it was shown that release of histamine followed injection of propanidid and thiopentone. Observations of gastric secretion, arterial pressure and pulse rate supported these findings. In normal persons the release of histamine had no special clinical significance. On the other hand, when ...


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