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In vivo analysis of RNA polymerase I elongation and termination in Saccharomyces cerevisiae

URN to cite this document:
Reiter, Alarich
Date of publication of this fulltext: 14 Sep 2011 08:46

Abstract (English)

RNA polymerase I (Pol I) is a specialized enzyme which transcribes the ribosomal RNA (rRNA) genes in all eukaryotes. Pol I transcription is regulated by specific DNA cis-elements and trans-acting factors as well as the usage of a specific chromatin template. Regulation and efficiency of rRNA synthesis in yeast depend on many processes including recruitment of the Pol I machinery and binding of ...


Translation of the abstract (German)

Die RNA Polymerase I (Pol I) ist ein spezialisiertes Enzym, welches die ribosomale RNA (rRNA) in allen Eukaryonten transkribiert. In die Regulation der Polymerase I Transkription sind spezielle DNA cis-Elemente, trans-agierende Faktoren sowie der Gebrauch einer besonderen Chromatinmatrize eingebunden. Die Effizienz und Regulation der rRNA Synthese ist bei der Hefe von vielen unterschiedlichen ...


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