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Die Bedeutung von Wachstumsfaktor-Rezeptortyrosinkinasen
der EGFR-Familie bei Plattenepithelkarzinomen
des Kopf-Hals-Bereichs

URN to cite this document:
urn:nbn:de:bvb:355-epub-220035
Brunner, Kathrin
Date of publication of this fulltext: 07 Sep 2011 13:41


Abstract (German)

Hintergrund: Untersuchungen von Rezeptortyrosinkinasen der humanen epidermalen Wachstumsfaktor-Rezeptor (HER)-Familie stehen im Fokus der modernen Tumorforschung. Die prognostische Bedeutung der HER-Rezeptoren in HNSCC (head and neck squamous cell carcinoma) wurde bislang kontrovers diskutiert. Methoden: In einem Kollektiv von insgesamt 242 HNSCC verschiedener Lokalisationen wurden alle vier ...

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Translation of the abstract (English)

Background: The HER (human epidermal growth factor receptor related) family has received considerable interest in modern cancer research. The prognostic value of HER-receptors in HNSCC (head and neck squamous cell carcinoma) has been discussed controversially. Methods: Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) for HER1-4 were performed in 242 cases of head and neck ...

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