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Renal effects of the new calcium channel blocking drug isradipine

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Krämer, Bernhard K. ; Häussler, M. ; Ress, K. M. ; Müller, G. A. ; Burger, K. J. ; Risler, T.
Date of publication of this fulltext: 08 Sep 2011 06:28


The acute effect of a single oral dose of isradipine 5 mg on blood pressure, renal haemodynamics, electrolyte excretion and plasma renin activity was studied in 10 healthy males. Isradipine did not produce a significant change in systolic or diastolic blood pressure, and glomerular filtration rate, renal plasma flow, renal vascular resistance, and urinary albumin excretion remained constant. ...


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