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New fluorescent probes and assays for lactate and hydrogen peroxide

URN to cite this document:
urn:nbn:de:bvb:355-epub-221733
Grögel, Dominik Berndt Michael
Date of publication of this fulltext: 28 Sep 2011 06:25


Abstract (English)

Novel fluorescent probes and methods for the determination of lactate and hydrogen peroxide (HP) are presented. The first part describes the design and preparation of two fluorescent probes for HP. The naphthalimide fluorophores 5 (which is referred to as HP Green) and 8 have either a p-anisidine (HP Green) or N,N-dimethyl-p-phenylene diamine (8) group attached as a redox active moiety. Both ...

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Translation of the abstract (German)

Im Rahmen dieser Arbeit werden neue fluoreszierende Farbstoffe und Methoden zur Bestimmung von Laktat und Wasserstoffperoxid (HP) vorgestellt. Der erste Teil beinhaltet die Synthese zweier neuer Farbstoffe für den Nachweis von HP. An die Naphthalimidfluorophore 5 (HP Green genannt) und 8 sind entweder p-Anisidin (HP Green) oder N,N-Dimethyl-p-phenylendiamin (8) als redoxaktive Gruppen gebunden. ...

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