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Differentiation between the Complement Modulating Effects of an Arabinogalactan-Protein from Echinacea purpurea and Heparin. (Dedicated to the 65th birthday of Prof. Dr. Gerhard Franz)

Alban, S. ; Classen, B. ; Brunner, G. ; Franz, Gerhard ; Blaschek, W.



Abstract

Due to the important physiological role of the complement system, complement modulation, either inhibition or stimulation, is an interesting target for drug development. Several plant polysaccharides are known to exhibit complement modulating activities. Sometimes these effects are described as complement inhibition, although the basic mechanism is a stimulation of the complement activation. This ...

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