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LaPSvS1, a (1→3)-β-galactan sulfate and its effect on angiogenesis in vivo and in vitro

Bürgermeister, Jutta ; Paper, Dietrich H. ; Vogl, Horst ; Linhardt, Robert J. ; Franz, Gerhard


LaPSvS1, a highly sulfated branched (1→3)-β-galactan was prepared from the arabino-galactan from Larix decidua Miller by partial hydrolysis and subsequent sulfation with SO3-pyridine in DMF. The molecular weight was analyzed by GPC and the sulfate content was determined by ion chromatography. LaPSvS1 exhibited good antiangiogenic and antiinflammatory effects in two different modifications of the ...


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