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Anticoagulant sulfated polysaccharides: Part I. Synthesis and structure–activity relationships of new pullulan sulfates

Alban, S., Schauerte, A. and Franz, Gerhard (2002) Anticoagulant sulfated polysaccharides: Part I. Synthesis and structure–activity relationships of new pullulan sulfates. Carbohydrate Polymers 47, pp. 267-276.

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Abstract

In order to develop new anticoagulants as potential heparin alternatives, two pullulans with different molecular weight (MW) were used as starting polymers for the partial synthesis of a structurally new class of sulfated polysaccharides. Sulfation of these linear α-1,4-/1,6-glucans was carried out by a method with a SO3–pyridine complex in DMF, which had been optimized for the modification of ...

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Item type:Article
Date:2002
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Franz
Identification Number:
ValueType
10.1016/S0144-8617(01)00178-3DOI
Keywords:Sulfated polysaccharides; Pullulan sulfates; Partial synthesis; Anticoagulant activity; Structure–activity relationships
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Item ID:22760
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