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Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering

Brandl, Ferdinand, Seitz, Anna Katharina, Teßmar, Jörg, Blunk, Torsten and Göpferich, Achim (2010) Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering. Biomaterials 31 (14), pp. 3957-3966.

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Adipose tissue engineering requires biomaterials that promote the differentiation of seeded adipocytes. Here, we report on the development and characterization of in situ forming, poly(ethylene glycol) (PEG) based hydrogels for soft tissue augmentation. Branched PEG-amines were modified with collagenase-sensitive peptides and cross-linked with branched PEG-succinimidyl propionates without the use ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
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Keywords:Adipose tissue engineering; Biomimetic material; Cell adhesion; Degradation; Hydrogel; Mechanical properties
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
600 Technology > 615 Pharmacy
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:23229
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