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Enzymatically degradable poly(ethylene glycol) based hydrogels for adipose tissue engineering

Brandl, Ferdinand ; Seitz, Anna Katharina ; Teßmar, Jörg ; Blunk, Torsten ; Göpferich, Achim


Adipose tissue engineering requires biomaterials that promote the differentiation of seeded adipocytes. Here, we report on the development and characterization of in situ forming, poly(ethylene glycol) (PEG) based hydrogels for soft tissue augmentation. Branched PEG-amines were modified with collagenase-sensitive peptides and cross-linked with branched PEG-succinimidyl propionates without the use ...


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