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Characterization of Colloidal Drug Carriers

URN to cite this document:
urn:nbn:de:bvb:355-epub-233135
Blunk, Torsten ; Mak, E. ; Müller, R. H.
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Date of publication of this fulltext: 27 Jan 2012 07:19


Abstract

Hydrophobic interaction chromatography (HIC) is presented as a suitable method to determine the surface hydrophobicity of colloidal drug carriers. The experimental design is described in great detail. Results obtained with surface-modified polystyrene particles as model carriers and parenteral fat emulsions are discussed as examples. HIC was able to distinguish between particles chemically ...

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