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Charakterisierung der Ficolin-B Expression in Immunzellen

Kürschner, Johanna Maria Theresia (2012) Charakterisierung der Ficolin-B Expression in Immunzellen. PhD, Universität Regensburg.

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Date of publication of this fulltext: 10 Feb 2012 07:52

Abstract (German)

Das angeborene Immunsystem verfügt über verschiedene Erkennungs- und Effektormechanismen, die einen wichtigen Beitrag für den Erfolg des gesamten Systems darstellen. Einer davon ist die Identifizierung pathogenspezifischer Strukturen, die u.a. über pattern recognition molecules (PRM) erfolgt, zu denen auch die Ficoline gehören. Dabei handelt es sich um Proteine, die sowohl kollagen- als auch ...

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Translation of the abstract (English)

Ficolins are pattern recognition molecules (PRM), which can identify certain pathogen associated structures. They are characterized by a collagen- and a fibrinogen-like domain. The fibrinogen-like domain binds to N-acetyl-glucosamine (GlcNAc). While in humans 3 types of Ficolins are known, there are two types of ficolins in rodents: Ficolin-A (serum-type protein) and Ficolin-B (non-serum-type ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:10 February 2012
Referee:Prof. Dr. Daniela Männel and Prof. Dr. Bernd Salzberger
Date of exam:27 January 2012
Institutions:Medicine > Lehrstuhl für Immunologie
Keywords:Ficolin-B, Ficolin, innate immunity, angeborene Immunität
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:23364
Owner only: item control page

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