Effects of DSP4 and methylphenidate on spatial memory performance in rats

URN to cite this document:: urn:nbn:de:bvb:355-epub-234987
DOI to cite this document:: 10.5283/epub.23498

Sontag, Thomas A. ; Hauser, Joachim ; Tucha, Oliver ; Lange, Klaus W.

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Date of publication of this fulltext: 24 Feb 2012 05:58

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Abstract

In this experiment, we have investigated the spatial memory performance of rats following a central noradrenaline depletion induced by three different doses of the neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP4) and following administration of three different doses of methylphenidate (MPH). The rats were required to find food pellets hidden on a holeboard. The sole administration ...