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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-237514
- DOI to cite this document:
- 10.5283/epub.23751
Abstract
Bestrophin-1 modulates currents through voltage-dependent L-type Ca2+ channels by physically interacting with the beta-subunits of Ca2+ channels. The main function of beta-subunits is to regulate the number of pore-forming Ca-V-subunits in the cell membrane and modulate Ca2+ channel currents. To understand the influence of full-length bestrophin-1 on beta-subunit function, we studied binding and ...

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