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Deep resequencing of the voltage-gated potassium channel subunit KCNE3 gene in chronic tinnitus.

URN to cite this document:
urn:nbn:de:bvb:355-epub-237564
Sand, Philipp G ; Langguth, Berthold ; Kleinjung, Tobias
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Date of publication of this fulltext: 11 Apr 2012 09:02


Abstract

Membrane-stabilizing drugs have long been used for the treatment of chronic tinnitus, suggesting an underlying disturbance of sensory excitability due to changes in ion conductance. The present study addresses the potassium channel subunit gene KCNE3 as a potential candidate for tinnitus susceptibility. 288 Caucasian outpatients with a diagnosis of chronic tinnitus were systematically screened ...

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