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Amino Acid Solvation in Aqueous Kosmotrope Solutions: Temperature Dependence of the L-Histidine-Glycerol Interaction

Kustov, Andrey V. ; Smirnova, Nataliya L. ; Neueder, Roland ; Kunz, Werner



Abstract

We have studied thermodynamics of interaction between the aromatic amino acid l-histidine and glycerol, which is one of the most important stabilizing agents for proteins in water. The pair and triplet interaction parameters have been extracted from enthalpy and solubility data using standard thermodynamic manipulations in a wide temperature range. Our results indicate for the first time that the ...

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