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Determining the cytotoxicity of catanionic surfactant mixtures on HeLa cells

Vlachy, Nina ; Touraud, Didier ; Heilmann, Jörg ; Kunz, Werner



Abstract

The cytotoxicity of commonly used synthetic surfactants and catanionic mixtures of those was evaluated using MTT on HeLa cells. The 50% inhibition concentration (IC(50)) for MTT reduction was calculated. The effect on chain length increase and inclusion of polyoxyethylene groups on the toxicity was tested on single surfactant systems. A general trend of increasing toxicity with increasing chain ...

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