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Establishment and maintenance of 35S rRNA gene chromatin states in Saccharomyces cerevisiae

Wittner, Manuel (2012) Establishment and maintenance of 35S rRNA gene chromatin states in Saccharomyces cerevisiae. PhD, Universität Regensburg.

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Date of publication of this fulltext: 24 May 2012 10:32

Abstract (English)

The ribosomal DNA (rDNA) locus of Saccharomyces cerevisiae (hereafter called yeast) represents an ideal model system to study the interplay between chromatin and all DNA-dependent processes such as transcription, replication and DNA repair. This multicopy gene locus harbours the 35S ribosomal RNA (rRNA) genes which are transcribed by the specialised RNA polymerase I (Pol I). Importantly, each 35S ...


Translation of the abstract (German)

Der ribosomale DNA (rDNA) Lokus von Saccharomyces cerevisiae (im weiteren Text Hefe genannt) repräsentiert ein ideales Modellsystem um das Zusammenspiel zwischen Chromatin und allen DNA-abhängigen Prozessen, wie z.B. der Transkription, der Replikation und der DNA Reparatur, zu untersuchen. Dieser Multikopien-Genlokus enthält die Gene für die 35S ribosomale RNA (rRNA), die durch die spezialisierte ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:24 May 2012
Referee:PD Dr. Joachim Giesenbeck and Prof. Dr. Michael Rehli and Prof. Dr. Wolfgang Seufert
Date of exam:16 May 2012
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III
Keywords:chromatin states, rRNA genes, transcription, replication, Hmo1, HMG-box protein NER, psoralen crosslinking
Dewey Decimal Classification:500 Science > 570 Life sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:24508
Owner only: item control page


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