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A two-step strategy for neuronal differentiation in vitro of human dental follicle cells

Völlner, Florian (2012) A two-step strategy for neuronal differentiation in vitro of human dental follicle cells. PhD, Universität Regensburg.

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Date of publication of this fulltext: 21 Jun 2012 06:36

Abstract (English)

Human dental follicle cells (DFCs) derived from wisdom teeth are precursor cells for cementoblasts. In this study, we recognized that naive DFCs express constitutively the early neural cell marker b-IIItubulin. Interestingly, DFCs formed b-III-tubulin-positive neurosphere-like cell clusters (NLCCs) on lowattachment cell culture dishes in serum-replacement medium (SRM). For a detailed examination ...


Translation of the abstract (German)

In der modernen Medizin ist der Einsatz von Stammzellen zunehmend unverzichtbar. So ermöglicht das Tissue Engineering durch die Kombination autolog gewonnener Zellen und biokompatibler Trägermaterialien heute bereits die Herstellung künstlicher Gewebe. Diese können als zur Unterstützung oder Substitution von degenerierten Geweben oder Organen in den Patienten replantiert werden. Dentale ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:21 June 2012
Referee:PD Dr. Christian Morsczeck and Prof. Dr. Dr. Joachim Grifka
Date of exam:14 May 2012
Institutions:Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Keywords:Differentiation, neuronal, human dental follicle cells
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:24957
Owner only: item control page


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