Neuroprotection by dopamine agonists

URN to cite this document:: urn:nbn:de:bvb:355-epub-254194
DOI to cite this document:: 10.5283/epub.25419

Lange, Klaus W. ; Rausch, W. D. ; Gsell, W. ; Naumann, M. ; Oestreicher, E. ; Riederer, P.

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Date of publication of this fulltext: 19 Jul 2012 07:39

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Abstract

Research on Parkinson's disease has led to new hypotheses concerning the mechanisms of neurodegeneration and to the development of neuroprotective agents. Recent findings of impaired mitochondrial function, altered iron metabolism and increased lipid peroxidation in the substantia nigra of parkinsonian patients emphasize the significance of oxidative stress and free radical formation in the ...