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MPTP-induced degeneration: interference with glutamatergic toxicity

URN to cite this document:
urn:nbn:de:bvb:355-epub-254202
Löschmann, P. A. ; Lange, Klaus W. ; Wachtel, H. ; Turski, L.
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Date of publication of this fulltext: 20 Jul 2012 11:54


Abstract

Parkinson's disease (PD) is characterised by the progressive degeneration of nigrostriatal dopamine (DA) neurons resulting in the major symptoms of akinesia and rigidity. Although the primary cause of PD is still not known some features make this disorder a model for neurodegenerative diseases in general. It has been known for some time that symptomatic PD can be attributed to insults with ...

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