Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

URN to cite this document:: urn:nbn:de:bvb:355-epub-254271

Sofic, E. ; Lange, Klaus W. ; Jellinger, K. ; Riederer, Peter

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Date of publication of this fulltext: 20 Jul 2012 11:24

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Abstract

Reduced and oxidized glutathione concentrations in post-mortem brain tissue from the substantia nigra of control subjects and patients with neuropathologically confirmed Parkinson's disease were measured by a coulometric method using high-pressure liquid chromatography and electrochemical detection. Reduced glutathione concentrations were decreased in the substantia nigra of parkinsonian patients ...