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Terguride stimulates locomotor activity at 2 months but not 10 months after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets

Lange, Klaus W., Löschmann, P. A,, Wachtel, H., Horowski, R., Jähnig, P., Jenner, P. and Marsden, C. D. (1992) Terguride stimulates locomotor activity at 2 months but not 10 months after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets. European journal of pharmacology 212 (2-3), pp. 247-252.

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Abstract

The mixed dopamine (DA) agonist/antagonist terguride acts as a DA antagonist on normosensitive receptors but shows DA agonistic properties at supersensitive DA receptors. Such a compound could offer an alternative to the treatment of Parkinson's disease with indirect or direct DA agonists. The present study compares the actions of terguride, 4-12 mg/kg i.p., in naive common marmosets with its ...

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Item type:Article
Date:1992
Institutions:Psychology and Pedagogy > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange
Identification Number:
ValueType
1350996PubMed ID
Classification:
NotationType
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineMESH
AnimalsMESH
Antiparkinson Agents/pharmacologyMESH
CallithrixMESH
Disease Models, AnimalMESH
Dopamine Agents/pharmacologyMESH
FemaleMESH
Lisuride/pharmacologyMESH
MaleMESH
Motor Activity/drug effectsMESH
Parkinson Disease, Secondary/drug therapyMESH
Time FactorsMESH
Dewey Decimal Classification:100 Philosophy & psychology > 150 Psychology
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:25430
Owner only: item control page

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