Glutamatergic-dopaminergic balance in the brain. Its importance in motor disorders and schizophrenia

URN to cite this document:: urn:nbn:de:bvb:355-epub-254335

Riederer, Peter ; Lange, Klaus W. ; Kornhuber, J. ; Danielczyk, W.

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Date of publication of this fulltext: 20 Jul 2012 11:13

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Abstract

Dopamine appears to be of less importance in the regulation of psychomotor functions than was previously thought. A central dopaminergic-glutamatergic balance may be important for both akinetic motor disorders and psychosis. In Parkinson's disease glutamate antagonists may counteract central glutamatergic hyperactivity and may be of value as anti-parkinsonian drugs. An increase of dopaminergic ...