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Neurotoxicity and neuroprotection in Parkinson's disease

Lange, Klaus W., Youdim, M. B. and Riederer, Peter (1992) Neurotoxicity and neuroprotection in Parkinson's disease. Journal of neural transmission. Supplementum supl. 38, pp. 27-44.

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Abstract

Recent findings of impaired mitochondrial function, altered iron metabolism and increased lipid peroxidation in the substantia nigra in Parkinson's disease emphasize the significance of oxidative stress and free radical formation in the pathogenesis of the disease. Future research will focus on improvements in neuroprotective therapy to prevent or slow the rate of progression of Parkinson's ...

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Item type:Article
Date:1992
Additional Information (public):ISBN des Bandes 3-211-82347-6, Titel "Advances in neuroscience and schizophrenia", hg. v. Tuma, A. H.
Institutions:Psychology and Pedagogy > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange
Identification Number:
ValueType
1491247PubMed ID
Classification:
NotationType
Antiparkinson Agents/therapeutic useMESH
Glutathione/metabolismMESH
HumansMESH
Iron/metabolismMESH
Melanins/metabolismMESH
Mitochondria/metabolismMESH
Neurotoxins/metabolismMESH
Oxidation-ReductionMESH
Parkinson Disease/metabolismMESH
Selegiline/therapeutic useMESH
Substantia Nigra/metabolismMESH
Dewey Decimal Classification:100 Philosophy & psychology > 150 Psychology
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:25435
Owner only: item control page

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