Neurotoxicity and neuroprotection in Parkinson's disease

URN to cite this document:: urn:nbn:de:bvb:355-epub-254356
DOI to cite this document:: 10.5283/epub.25435

Lange, Klaus W. ; Youdim, M. B. ; Riederer, Peter

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Date of publication of this fulltext: 20 Jul 2012 11:47

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Abstract

Recent findings of impaired mitochondrial function, altered iron metabolism and increased lipid peroxidation in the substantia nigra in Parkinson's disease emphasize the significance of oxidative stress and free radical formation in the pathogenesis of the disease. Future research will focus on improvements in neuroprotective therapy to prevent or slow the rate of progression of Parkinson's ...