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Glutamate receptor antagonism: neurotoxicity, anti-akinetic effects, and psychosis

Riederer, Peter, Lange, Klaus W., Kornhuber, J. and Jellinger, K. (1991) Glutamate receptor antagonism: neurotoxicity, anti-akinetic effects, and psychosis. Journal of neural transmission. Supplementum supl. 34, pp. 203-210.

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Abstract

There is evidence to suggest that glutamate and other excitatory amino acids play an important role in the regulation of neuronal excitation. Glutamate receptor stimulation leads to a non-physiological increase of intracellular free Ca2+. Disturbed Ca2+ homeostasis and subsequent radical formation may be decisive factors in the pathogenesis of neurodegenerative diseases. Decreased glutamatergic ...

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Item type:Article
Date:1991
Additional Information (public):ISBN des Bandes 3-211-82261-5, Titel " Age-associated neurological diseases", hg. v. Deecke, L.
Institutions:Psychology and Pedagogy > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange
Identification Number:
ValueType
1687783PubMed ID
Classification:
NotationType
AnimalsMESH
Glutamates/toxicityMESH
Glutamic AcidMESH
HumansMESH
Models, NeurologicalMESH
Models, PsychologicalMESH
Nerve Degeneration/drug effectsMESH
Neurons/physiologyMESH
Neurotoxins/toxicityMESH
Psychotic Disorders/physiopathologyMESH
Receptors, GlutamateMESH
Receptors, Neurotransmitter/physiologyMESH
Schizophrenia/physiopathologyMESH
Dewey Decimal Classification:100 Philosophy & psychology > 150 Psychology
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:25440
Owner only: item control page

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