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Bedeutung des Neurotoxins MPTP für Ätiologie und Therapie der idiopathischen Parkinsonkrankheit [Significance of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine for the etiology and therapy of idiopathic Parkinson disease]

Lange, Klaus W. (1989) Bedeutung des Neurotoxins MPTP für Ätiologie und Therapie der idiopathischen Parkinsonkrankheit [Significance of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine for the etiology and therapy of idiopathic Parkinson disease]. Fortschritte der Neurologie-Psychiatrie 57 (4), pp. 142-148.

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Abstract

Exposure of drug addicts to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) has caused a Parkinsonian syndrome accompanied by a selective destruction of dopamine containing neurones in the pars compacta of the substantia nigra. MPTP in the human causes a severe irreversible state that very closely resembles idiopathic Parkinson's disease both in its clinical features and response to ...

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Item type:Article
Date:1989
Institutions:Psychology and Pedagogy > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange
Identification Number:
ValueType
2656447PubMed ID
10.1055/s-2007-1000755DOI
Classification:
NotationType
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineMESH
AnimalsMESH
Antiparkinson Agents/therapeutic useMESH
Disease Models, AnimalMESH
HumansMESH
Locus Coeruleus/drug effectsMESH
Parkinson Disease, Secondary/drug therapyMESH
Pyridines/adverse effectsMESH
Receptors, Dopamine/drug effectsMESH
Substantia Nigra/drug effectsMESH
Dewey Decimal Classification:100 Philosophy & psychology > 150 Psychology
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:25447
Owner only: item control page

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